Rejuran Explained: Salmon-DNA PN Repair for Stronger Skin
What polynucleotides actually do, who benefits most, and what a realistic course looks like.
Rejuran is one of the most searched skin treatments in Thailand — and one of the most misunderstood. It is not a filler and not a whitening shot. It is a polynucleotide (PN) injectable that gives skin the raw material to repair itself: calmer, stronger, better-hydrated skin over weeks, not overnight.
What is Rejuran?
Rejuran is an injectable of purified polynucleotides (PN) — DNA fragments extracted from salmon, chosen because they are highly compatible with human tissue. Placed as microdroplets in the skin, PN acts as a repair signal and building material: it supports fibroblast activity, calms inflammation and improves the skin's own regeneration cycle.
Because it works with your skin's own biology, the change is gradual and natural-looking — people tend to notice skin that is less reactive, smoother at the pores, and healthier in tone rather than a dramatic single-day difference.
What Rejuran helps with
Doctors reach for PN when the problem is skin quality and resilience rather than volume or shape. Typical goals include:
- Weak, thin or easily-irritated skin that flushes or breaks out easily
- Enlarged-looking pores and rough texture
- Early fine lines, especially around the eyes
- Post-acne redness and shallow acne scars (as part of a scar plan)
- Dull, tired-looking skin that lost its healthy glow
How many sessions, and when do results show?
A standard starting course is 3–4 sessions spaced 2–4 weeks apart, then a maintenance session every few months. Skin feels better hydrated within the first weeks; texture, pore appearance and resilience improve progressively over 1–3 months as regeneration catches up.
At Hori, the doctor examines your skin first — depth, technique and pairing (for example with lasers or other boosters) are adjusted to the actual problem, not a fixed menu.
Aftercare — the first 48 hours
- Expect small bumps at injection points — they settle within 24–48 hours
- Skip makeup on the treated area for the rest of the day
- Avoid saunas, heavy exercise and swimming for 24–48 hours
- Moisturise and use sunscreen daily — sun protection protects the result
- Bruising, if any, is small and fades within days
The short version
- Rejuran = PN repair — it rebuilds skin quality, not shape or volume.
- Best for weak, thin, easily-irritated skin, pores, fine lines and post-acne texture.
- Plan for a 3–4 session course; results build over 1–3 months and look natural.
Frequently asked questions
Does Rejuran hurt?+
There is a stinging sensation, but numbing cream and fine-needle or injector techniques keep it very tolerable. Most people rate it mild.
How is Rejuran different from Vitaran?+
Both are polynucleotide boosters. Rejuran is the original Korean PN focused on repair and resilience; Vitaran emphasises hydration and glow. Your doctor matches the product to your skin goal.
How long do results last?+
After a full course, improvements typically hold for around 6–12 months depending on age, sun exposure and lifestyle. A maintenance session every few months keeps skin in its best state.
Can Rejuran treat acne scars alone?+
For shallow texture it helps, but true rolling or boxcar scars respond best when PN is combined with subcision, laser or other scar techniques in a staged plan.
Who should avoid Rejuran?+
People with fish/salmon allergy, active infection at the area, pregnancy or breastfeeding should consult the doctor first — alternatives can usually be found.
